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5-[(2R)-2-(2,5-Difluorophenyl)-1-pyrrolidinyl]-3-nitropyrazolo[1,5-a]pyrimidine

  • CasNO.:1223404-90-7
  • ProductCode:HPC033
Details

MolecularFormula:C16H13F2N5O2Melting Point:
Molecular Weight:345.30Packaging:
Appearance:ProductionCapacity:Kgs~Tons
Purity:99%+Productuse:

Larotrectinib sulfate Intermediate

Larotrectinib (LOXO-101) sulfate is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).

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