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Product Detail

  • Tucatinib
  • Tucatinib
  • Tucatinib
  • Tucatinib


  • CAS No.937263-43-9:
  • Molecular Formula:C26H24N8O2:
  • Molecular Weight:480.5:
  • Reference Standard:In-house:
  • Documentation:TP:
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Product Description

Tucatinib is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. Tucatinib selectively binds to and inhibits the phosphorylation of ErbB-2, which may prevent the activation of ErbB-2 signal transduction pathways, resulting in growth inhibition and death of ErbB-2-expressing tumor cells. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation.

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