Tivozanib Hydrochloride
- CAS No.682745-41-1:
- Molecular Formula:C22H22Cl2N4O6:
- Molecular Weight:509.34:
- Reference Standard:In-house:
- Documentation:China DMF:
- Inquiry
Product Description
Tivozanib is a tyrosine kinase inhibitor. In vitro cellular kinase assays have shown that tivozanib inhibits phosphorylation of vascular endothelial growth factor receptor (VEGFR)-1, VEGFR-2 and VEGFR-3 at clinically relevant concentrations and inhibits other kinases, including c-kit and PDGFRβ. as well as tumor growth in various tumor cell types, including human renal cell carcinoma.
Hits: 【Print】