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  • Ruxolitinib Phosphate
  • Ruxolitinib Phosphate
  • Ruxolitinib Phosphate
  • Ruxolitinib Phosphate

Ruxolitinib Phosphate

  • CAS No.1092939-17-7:
  • Molecular Formula:C17H21N6O4P:
  • Molecular Weight:404.4:
  • Reference Standard:In-house:
  • Documentation:TP:
  • Inqury

Product Description

Ruxolitinib Phosphate is the phosphate salt form of ruxolitinib, an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.

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