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Product Detail

  • Molnupiravir
  • Molnupiravir
  • Molnupiravir
  • Molnupiravir

Molnupiravir

  • CAS No.2349386-89-4:
  • Molecular Formula:C13H19N3O7:
  • Molecular Weight:329.31:
  • Reference Standard:In-house:
  • Documentation:China DMF:
  • Inquiry

Product Description

Molnupiravir is the isopropylester prodrug of [N4-hydroxycytidine]. With improved oral bioavailability in non human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as viral error catastrophe. Recent studies have shown EIDD-2801 inhibits replication of human and bat coronaviruses, including SARS-CoV-2, in mice and human airway epithelial cells. A [remdesivir] resistant mutant mouse hepatitis virus has also been shown to have increased sensitivity to N4-hydroxycytidine.

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